Annual report pursuant to Section 13 and 15(d)

Share-Based Compensation (Details - Employee option activity)

v3.22.1
Share-Based Compensation (Details - Employee option activity) - Share-based Payment Arrangement, Option [Member] - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Options outstanding, beginning balance 763,722 662,059
Weighted-average exercise price outstanding, beginning balance $ 8.01 $ 10.88
Weighted-average remaining life outstanding beginning 8 years 8 months 4 days 9 years 4 months 2 days
Aggregate intrinsic value, outstanding beginning balance $ 498,625 $ 66,125
Options granted 325,000 125,000
Weighted-average exercise price, granted $ 2.15 $ 1.10
Options expired 0 (23,337)
Weighted-average exercise price, expired $ 52.55
Options expired 0 23,337
Options outstanding, ending balance 1,088,722 763,722
Weighted-average exercise price, ending balance $ 6.26 $ 8.01
Weighted-average remaining life outstanding ending 8 years 2 months 19 days  
Aggregate intrinsic value, outstanding ending balance $ 23,750 $ 498,625
Options vested or expected to vest 1,088,722  
Weighted-average exercise price, vested or expected to vest $ 6.26  
Weighted-average remaining life, vested or expected to vest 8 years 2 months 19 days  
Aggregate intrinsic value, vested or expected to vest $ 23,750  
Options exercisable 630,357 372,042
Weighted-average exercise price, exercisable $ 9.42 $ 15.12
Weighted-average remaining life, exercisable 7 years 7 months 17 days 8 years 1 month 2 days
Aggregate intrinsic value, exercisable $ 23,750 $ 186,449