Annual report pursuant to Section 13 and 15(d)

Share-Based Expense (Details - Share based expense)

v3.22.1
Share-Based Expense (Details - Share based expense) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]    
Share-based compensation $ 410,437 $ 468,914
Research and Development Expense [Member]    
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]    
Share-based compensation 68,208 49,190
General and Administrative Expense [Member]    
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]    
Share-based compensation $ 342,229 $ 419,724