Annual report pursuant to Section 13 and 15(d)

10. Income Taxes (Details - Tax reconcilation)

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10. Income Taxes (Details - Tax reconcilation) - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Income Tax Disclosure [Abstract]    
Federal $ (18,429,763) $ (4,252,540)
State (455,191) (276,601)
Increase in tax losses not recognized 9,751,401 2,238,879
Permanent differences, net 780,836 800,891
Mark to market 992,621 722,540
Foreign rate differential 6,923,116 502,357
Share-based payments, net 524,131 308,888
Enhanced research and development tax credits (87,151) (44,414)
Net provision (benefit) for income taxes $ 0 $ 0