Annual report pursuant to Section 13 and 15(d)

Income Taxes - Reconciliation of Income Tax Expense (Benefit) (Detail)

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Income Taxes - Reconciliation of Income Tax Expense (Benefit) (Detail) - USD ($)
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Income Tax Disclosure [Abstract]    
UK corporation tax benefit at statutory rate $ (1,994,675) $ (1,550,443)
Increase in tax losses not recognized 1,461,836 1,319,946
Permanent differences, net 674,920 99,825
Foreign rate differential (100,131) (89,442)
Share-based compensation, net 9,179 6,770
Other $ 163 6,531
Impairment of IPR&D   266,471
Enhanced research and development tax credits $ (51,292) $ (59,658)
Net expense (benefit) for income taxes