Annual report pursuant to Section 13 and 15(d)

2. Summary of Significant Accounting Policies (Details Narrative)

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2. Summary of Significant Accounting Policies (Details Narrative) - USD ($)
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Basis Of Presentation And Significant Accounting Policies [Line Items]    
Comprehensive loss adjustment due to correction of accounting for foreign currency matters in a prior period $ 240,000  
Accumulated other comprehensive loss adjustment due to correction of accounting for foreign currency matters in a prior period 310,000  
Letter of credit $ 66,000  
Letter of credit purpose Required for operating lease for office and laboratory space in Lexington, Massachusetts.  
Impairment of indefinate lived intangible assets $ 0 $ 0
Impairment of goodwill 0 0
Impairment of long-lived assets $ 0 $ 0
Antidilutive shares 12,030,000 11,870,000
JSOP [Member]    
Basis Of Presentation And Significant Accounting Policies [Line Items]    
JSOP awards issued 10,688,194