Annual report pursuant to Section 13 and 15(d)

11. Stockholders' Equity (Details Narrative)

11. Stockholders' Equity (Details Narrative) - USD ($)	2 Months Ended	6 Months Ended		7 Months Ended			11 Months Ended	12 Months Ended
11. Stockholders' Equity (Details Narrative) - USD ($)	Mar. 05, 2019	Jul. 03, 2019	Jun. 25, 2019	Jul. 19, 2019	Jul. 17, 2019	Jul. 16, 2019	Dec. 10, 2020	Dec. 31, 2020	Dec. 31, 2019	Dec. 04, 2020
Common stock, shares authorized								50,000,000	12,500,000	50,000,000
Reverse stock split			1-for-12 reverse stock split
Reverse stock split, shares			1,442
Net proceeds from issuance of common stock								$ 5,426,825	$ 0
Net proceeds from issuance of common stock and warrants in public offering								0	13,421,950
Net proceeds from issuance of common stock and warrants in registered direct offering								$ 0	$ 2,699,050
Stock outstanding								8,745,207	6,065,441
Proceeds from warrants exercised								$ 0	$ 6,209
Deemed dividend related to Series B Preferred Stock down round provision, value								$ 0	$ 5,284,379
Preferred stock authorized								10,000,000	10,000,000
Share-based compensation								$ 468,914	$ 853,517
General and administrative expense								$ 3,400,071	$ 4,731,176
Warrants [Member]
Warrants outstanding								30,307	32,412
Warrants [Member] \| Debt and Equity Financing Warrants [Member]
Warrants issued								0	0
Warrant exercise price								$ 50.20	$ 51.97
Warrants exercised, shares								0	0
Warrants outstanding								212,185	262,690
Warrant expiration dates								March 2021 through November 2021
SynBio 2014 Warrant [Member]
Warrants expired									17,033
Share-based compensation									$ 0
SynBio Partner Warrants [Member]
Warrants expired									809
Serum Institute 2014 Warrant [Member]
Warrants expired									8,081
Serum Institute Partner Warrants [Member]
Warrants expired									410
Serum Institute Warrants [Member]
Warrants outstanding								17,677
Collaboration Warrants [Member]
Warrants issued								0	0
Warrants exercised, shares								0	0
Warrants expired								2,105	12,532
Warrants weighted average exercise price								$ 124.74
Warrant expiration dates								April 2021 through May 2021
Consent Warrants [Member]
Warrants issued		8,335
Warrant exercise price		$ 10.63
Grant date fair value of warrants per share		$ 7.62
Warrants granted fair value		$ 64,000
Modification for July 2019 Offering [Member] \| Consent Warrants [Member]
Warrant exercise price				$ 2.91
Fair value adjustment of warrants				$ 2,000
Series A Preferred Stock [Member]
Preferred stock authorized								1,000,000
Preferred stock stated value per share								$ 4.80
If converted, common stock issuable								80,834
Stock converted, shares converted								0	0
Series B Preferred Stock [Member]
Deemed dividend related to Series B Preferred Stock down round provision, value									$ 5,300,000
Preferred stock authorized								2,500,000
Preferred stock stated value per share								$ 4.00
If converted, common stock issuable								600,000
Stock converted, shares converted								0	0
2020 Offering [Member] \| Common Stock [Member
Sale of stock, shares issued							2,448,980
Stock sale price							$ 2.45
Net proceeds from issuance of common stock							$ 5,400,000
July 2019 Offering [Member]
Gross proceeds form the sale of stock and warrants					$ 15,000,000
Net proceeds from issuance of common stock and warrants in public offering					13,400,000
July 2019 Offering [Member] \| Overallotment Option [Member]
Gross proceeds form the sale of stock and warrants					$ 1,600
July 2019 Offering [Member] \| Common Stock [Member
Sale of stock, shares issued					1,730,000
July 2019 Offering [Member] \| Prefunded Warrants [Member]
Prefunded warrants issued					570,000
Warrant exercise price					$ 0.01
Warrants exercisable as of date					Jul. 17, 2019
Warrants exercised, shares									200,000
Proceeds from warrants exercised									$ 5,700
Intrinsic value of warrants					$ 3,100,000
July 2019 Offering [Member] \| Purchase Warrants [Member]
Warrants issued					2,300,000
Warrant exercise price					$ 13.00
Warrant term					5 years
Grant date fair value of warrants per share					$ 4.61
Warrants exercised, shares								2,200,000
Warrants granted fair value					$ 11,300,000
Warrants outstanding								29,000
July 2019 Offering [Member] \| Common Stock and Purchase Warrant [Member]
Stock sale price					$ 6.50
July 2019 Offering [Member] \| Prefunded Warrant and Purchase Warrant [Member]
Stock sale price					$ 6.49
July 2019 Offering [Member] \| Additional Securities [Member]
Sale of stock, shares issued					345,000
Underwriting Agreement [Member] \| Consent Shares [Member] \| Certain Holders of Warrants [Member]
Sale of stock, shares issued						16,666
March 2019 Offering [Member]
Net proceeds from issuance of common stock and warrants in registered direct offering	$ 2,700,000
March 2019 Offering [Member] \| Common Stock [Member
Sale of stock, shares issued	86,667
Stock sale price	$ 24.00
March 2019 Offering [Member] \| Prefunded Warrants [Member]
Prefunded warrants issued	42,417
Warrant exercise price	$ 0.012
Warrants exercisable as of date	Mar. 07, 2019
Stock sale price	$ 23.988
Proceeds from warrants exercised									$ 509
Warrants outstanding								42,417
March 2019 Offering [Member] \| Warrant and Prefunded Warrant [Member] \| Private Placement [Member]
Warrant exercise price	$ 27.00
Warrants exercisable as of date	Sep. 08, 2019
Warrant term	7 years
Grant date fair value of warrants per share	$ 22.74
Warrants granted fair value	$ 2,900,000
Intrinsic value of warrants	$ 1,100,000