Annual report pursuant to Section 13 and 15(d)

Cover
- Document and Entity Information
Financial Statements
Notes to Financial Statements
Accounting Policies
- 3. Summary of Significant Accounting Policies (Policies)
Notes Tables
Notes Details

4. Significant Strategic Collaborations (Details Narrative)

v3.20.4

4. Significant Strategic Collaborations (Details Narrative) - USD ($)	3 Months Ended	12 Months Ended
	Sep. 30, 2019	Dec. 31, 2020	Dec. 31, 2019
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Revenue		$ 436,942	$ 17,066
Research and development expenses		1,731,406	4,889,340
Prepaid expenses and other		200,000	700,000
MSA [Member]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Prepaid expenses and other		$ 25,000	100,000
Pharmsynthez [Member] \| Series B Preferred Stock [Member]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Warrants outstanding		1,500,000
Takeda [Member] \| Royalty Revenue [Member]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Revenue		$ 437,000	$ 17,000
Scripps Research [Member]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research and development expenses		$ 900,000
Pharmsynthez [Member]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research and development expenses	$ 350,000
Percent ownership in Xenetic		5.10%	7.40%
Pharmsynthez [Member] \| MSA [Member]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research and development expenses		$ 200,000
Pharmsynthez [Member] \| Work Order [Member]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Milestone payment		50,000
SynBio [Member] \| Co-Development Agreement [Member] \| Research, development, license and supply agreement [Member]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Revenue		$ 0	$ 0

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