Quarterly report pursuant to Section 13 or 15(d)

8. Stockholders' Equity (Details Narrative)

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8. Stockholders' Equity (Details Narrative) - $ / shares
3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Dec. 31, 2020
Colllaboration Warrants [Member]      
Warrants outstanding 30,307   30,307
Warrants weighted average exercise price $ 124.74   $ 124.74
Warrant expiration dates April 2021 through May 2021    
Warrants granted 0 0  
Warrants exercised 0 0  
Debt and Equity Financing Warrants [Member]      
Warrants outstanding 347,505   378,453
Warrants weighted average exercise price $ 36.74   $ 36.74
Warrant expiration dates July 2021 through September 2026    
Warrants exercised 1,485 200,000  
Warrants expired 29,000 0