Condensed Consolidated Statements Of Changes In Stockholders' Equity (Unaudited) - USD ($)
|
Preferred Stock |
Common Stock [Member] |
Additional Paid-In Capital |
Accumulated Deficit |
Accumulated Other Comprehensive Income |
Treasury Stock |
Total |
Beginning balance, shares at Dec. 31, 2017 |
3,090,742
|
753,659
|
|
|
|
|
|
Beginning balance, value at Dec. 31, 2017 |
$ 3,090
|
$ 754
|
$ 165,258,198
|
$ (145,933,137)
|
$ 253,734
|
$ (5,281,180)
|
$ 14,301,459
|
Exercise of warrants, shares |
|
30,834
|
|
|
|
|
|
Exercise of warrants, value |
|
$ 31
|
1,479,969
|
|
|
|
1,480,000
|
Conversion of Series B preferred stock to shares of common stock, shares |
(316,348)
|
26,363
|
|
|
|
|
|
Conversion of Series B preferred stock to shares of common stock, value |
$ (316)
|
$ 26
|
290
|
|
|
|
|
Share-based expense |
|
|
1,123,000
|
|
|
|
1,123,000
|
Common stock awards to vendors |
|
|
52,281
|
|
|
|
52,281
|
Net loss |
|
|
|
(5,661,230)
|
|
|
(5,661,230)
|
Ending balance, shares at Sep. 30, 2018 |
2,774,394
|
810,856
|
|
|
|
|
|
Ending balance, value at Sep. 30, 2018 |
$ 2,774
|
$ 811
|
167,913,738
|
(151,594,367)
|
253,734
|
(5,281,180)
|
11,295,510
|
Beginning balance, shares at Jun. 30, 2018 |
2,774,394
|
810,856
|
|
|
|
|
|
Beginning balance, value at Jun. 30, 2018 |
$ 2,774
|
$ 811
|
167,590,260
|
(149,781,831)
|
253,734
|
(5,281,180)
|
12,784,568
|
Share-based expense |
|
|
306,051
|
|
|
|
306,051
|
Common stock awards to vendors |
|
|
17,427
|
|
|
|
17,427
|
Net loss |
|
|
|
(1,812,536)
|
|
|
(1,812,536)
|
Ending balance, shares at Sep. 30, 2018 |
2,774,394
|
810,856
|
|
|
|
|
|
Ending balance, value at Sep. 30, 2018 |
$ 2,774
|
$ 811
|
167,913,738
|
(151,594,367)
|
253,734
|
(5,281,180)
|
11,295,510
|
Beginning balance, shares at Dec. 31, 2018 |
2,774,394
|
810,856
|
|
|
|
|
|
Beginning balance, value at Dec. 31, 2018 |
$ 2,774
|
$ 811
|
168,170,244
|
(153,233,595)
|
253,734
|
(5,281,180)
|
9,912,788
|
Issuance of common stock and warrants in registered direct offering, net of issuance costs, shares |
|
86,667
|
|
|
|
|
|
Issuance of common stock and warrants in registered direct offering, net of issuance costs, value |
|
$ 87
|
2,698,963
|
|
|
|
2,699,050
|
Issuance of common stock and warrants in public offering, net of issuance costs, shares |
|
1,746,666
|
|
|
|
|
|
Issuance of common stock and warrants in public offering, net of issuance costs, value |
|
$ 1,747
|
13,420,203
|
|
|
|
13,421,950
|
Issuance of common stock in connection with purchase of in-process research and development, shares |
|
624,995
|
|
|
|
|
|
Issuance of common stock in connection with purchase of in-process research and development, value |
|
$ 625
|
3,030,601
|
|
|
|
3,031,226
|
Exercise of pre-funded warrants, shares |
|
492,417
|
|
|
|
|
|
Exercise of pre-funded warrant, value |
|
$ 492
|
4,517
|
|
|
|
5,009
|
Exercise of purchase warrants, shares |
|
1,889,602
|
|
|
|
|
|
Exercise of purchase warrants, value |
|
$ 1,890
|
(1,890)
|
|
|
|
|
Issuance of common stock to vendor, shares |
|
7,836
|
|
|
|
|
|
Issuance of common stock to vendor, value |
|
$ 7
|
(7)
|
|
|
|
|
Issuance of warrants in connection with reverse stock split, shares |
|
|
|
|
|
|
|
Issuance of warrants in connection with reverse stock split, value |
|
|
63,536
|
|
|
|
63,536
|
Issuance of common stock to adjust for reverse split rounding, shares |
|
1,442
|
|
|
|
|
|
Issuance of common stock to adjust for reverse split rounding, value |
|
$ 1
|
(1)
|
|
|
|
|
Deemed dividend related to Series B Preferred Stock down round provision |
|
|
5,284,379
|
|
|
|
5,284,379
|
Accretion of deemed dividend related to Series B Preferred Stock down round provision |
|
|
(5,284,379)
|
|
|
|
(5,284,379)
|
Share-based expense |
|
|
683,104
|
|
|
|
683,104
|
Common stock awards to vendors |
|
|
47,427
|
|
|
|
47,427
|
Net loss |
|
|
|
(11,604,778)
|
|
|
(11,604,778)
|
Ending balance, shares at Sep. 30, 2019 |
2,774,394
|
5,660,481
|
|
|
|
|
|
Ending balance, value at Sep. 30, 2019 |
$ 2,774
|
$ 5,660
|
188,116,697
|
(164,838,373)
|
253,734
|
(5,281,180)
|
18,259,312
|
Beginning balance, shares at Jun. 30, 2019 |
2,774,394
|
949,218
|
|
|
|
|
|
Beginning balance, value at Jun. 30, 2019 |
$ 2,774
|
$ 948
|
171,352,760
|
(155,938,245)
|
253,734
|
(5,281,180)
|
10,390,791
|
Issuance of common stock and warrants in public offering, net of issuance costs, shares |
|
1,746,666
|
|
|
|
|
|
Issuance of common stock and warrants in public offering, net of issuance costs, value |
|
$ 1,747
|
13,420,203
|
|
|
|
13,421,950
|
Issuance of common stock in connection with purchase of in-process research and development, shares |
|
624,995
|
|
|
|
|
|
Issuance of common stock in connection with purchase of in-process research and development, value |
|
$ 625
|
3,030,601
|
|
|
|
3,031,226
|
Exercise of pre-funded warrants, shares |
|
450,000
|
|
|
|
|
|
Exercise of pre-funded warrant, value |
|
$ 450
|
4,050
|
|
|
|
4,500
|
Exercise of purchase warrants, shares |
|
1,889,602
|
|
|
|
|
|
Exercise of purchase warrants, value |
|
$ 1,890
|
(1,890)
|
|
|
|
|
Issuance of warrants in connection with reverse stock split, shares |
|
|
|
|
|
|
|
Issuance of warrants in connection with reverse stock split, value |
|
|
63,536
|
|
|
|
63,536
|
Deemed dividend related to Series B Preferred Stock down round provision |
|
|
1,404,932
|
|
|
|
1,404,932
|
Accretion of deemed dividend related to Series B Preferred Stock down round provision |
|
|
(1,404,932)
|
|
|
|
(1,404,932)
|
Share-based expense |
|
|
232,437
|
|
|
|
232,437
|
Common stock awards to vendors |
|
|
15,000
|
|
|
|
15,000
|
Net loss |
|
|
|
(8,900,128)
|
|
|
(8,900,128)
|
Ending balance, shares at Sep. 30, 2019 |
2,774,394
|
5,660,481
|
|
|
|
|
|
Ending balance, value at Sep. 30, 2019 |
$ 2,774
|
$ 5,660
|
$ 188,116,697
|
$ (164,838,373)
|
$ 253,734
|
$ (5,281,180)
|
$ 18,259,312
|