Annual report pursuant to Section 13 and 15(d)

Cover
- Document and Entity Information
Financial Statements
Notes to Financial Statements
Accounting Policies
- 2. Summary of Significant Accounting Policies (Policies)
Notes Tables
Notes Details

8. Hybrid Debt Instrument (Details Narrative)

v3.8.0.1

8. Hybrid Debt Instrument (Details Narrative) - USD ($)	12 Months Ended
8. Hybrid Debt Instrument (Details Narrative) - USD ($)	Dec. 31, 2017	Dec. 31, 2016
Loss on issuance of hybrid debt instruments	$ 0	$ (1,690,784)
Gain (loss) on extinguishment of debt	$ 0	(6,394,921)
Initial APA Note [Member] \| Pharmsynthez and Kevelt [Member]
Convertible note face value		3,500,000
Loss on issuance of hybrid debt instruments		(1,600,000)
Gain on change in fair value of hybrid instrument		$ 1,900,000
Hybrid Debt Instrument [Member] \| Pharmsynthez [Member]
Devt converted, shares issued		1,400,000
Debt converted, debt amount		$ 6,500,000
Debt converted, interest converted		200,000
Gain (loss) on extinguishment of debt		(6,200,000)
Additional APA Note [Member] \| Pharmsynthez [Member]
Convertible note face value		$ 500,000
Conversion price		$ 4.95
Warrants issued		50,506
CEO Note [Member] \| M. Scott Maguire [Member]
Convertible note face value		$ 369,958
Warrants issued		37,369
Interest expense		$ 13,176
Further Notes [Member] \| Note 1 [Member]
Convertible note face value		$ 178,000
Conversion price		$ 4.00
Further Notes [Member] \| Note 2 [Member]
Convertible note face value		$ 322,000
Conversion price		$ 4.00
Period Notes [Member]
Gain on change in fair value of hybrid instrument		$ (100,000)
All Notes [Member]
Interest expense		$ 700,000

- Definition

Amount of gain (loss) from the increase (decrease) in fair value of derivative and nonderivative instruments designated as fair value hedging instruments recognized in the income statement.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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-SubTopic 25
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+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
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The price per share of the conversion feature embedded in the debt instrument.

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- Definition

Face (par) amount of debt instrument at time of issuance.

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- Definition

Difference between the fair value of payments made and the carrying amount of debt which is extinguished prior to maturity.

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Amount of the cost of borrowed funds accounted for as interest expense for debt.

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- Definition

Warrants issued, shares

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