8. Share-Based Compensation (Details - Share based compensation) - USD ($)  | 
3 Months Ended | 6 Months Ended | ||
|---|---|---|---|---|
Jun. 30, 2016  | 
Jun. 30, 2015  | 
Jun. 30, 2016  | 
Jun. 30, 2015  | 
|
| Share-based compensation | $ 1,731,803 | $ 89,970 | $ 2,018,263 | $ 238,198 | 
| Research and Development Expense [Member] | ||||
| Share-based compensation | 1,427,691 | 51,736 | 1,234,240 | 150,881 | 
| Administrative Expense [Member] | ||||
| Share-based compensation | $ 304,112 | $ 38,234 | $ 784,023 | $ 86,317 | 
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- Definition Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees. Reference 1: http://www.xbrl.org/2003/role/presentationRef 
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