Quarterly report pursuant to Section 13 or 15(d)

Condensed Consolidated Statements of Changes in Stockholders' Equity

Condensed Consolidated Statements of Changes in Stockholders' Equity - USD ($)	Preferred Stock	Common Stock	Additional Paid-In Capital	Accumulated Deficit	Other Comprehensive Income / Loss	Treasury Stock	Total
Beginning balance, shares at Dec. 31, 2017	3,090,742	753,659
Beginning balance, value at Dec. 31, 2017	$ 3,090	$ 754	$ 165,258,198	$ (145,933,137)	$ 253,734	$ (5,281,180)	$ 14,301,459
Exercise of warrants, shares		30,834
Exercise of warrants, value		$ 31	1,479,969				1,480,000
Conversion of Series B preferred stock to shares of common stock, shares	(316,348)	26,363
Conversion of Series B preferred stock to shares of common stock, value	$ (316)	$ 26	290
Share-based expense			816,949				816,949
Common stock awards to vendors			34,854				34,854
Net loss				(3,848,694)			(3,848,694)
Ending balance, shares at Jun. 30, 2018	2,774,394	810,856
Ending balance, value at Jun. 30, 2018	$ 2,774	$ 811	167,590,260	(149,781,831)	253,734	(5,281,180)	12,784,568
Beginning balance, shares at Mar. 31, 2018	3,090,742	753,659
Beginning balance, value at Mar. 31, 2018	$ 3,090	$ 754	165,664,392	(147,755,655)	253,734	(5,281,180)	12,885,135
Exercise of warrants, shares		30,834
Exercise of warrants, value		$ 31	1,479,969				1,480,000
Conversion of Series B preferred stock to shares of common stock, shares	(316,348)	26,363
Conversion of Series B preferred stock to shares of common stock, value	$ (316)	$ 26	290
Share-based expense			428,182				428,182
Common stock awards to vendors			17,427				17,427
Net loss				(2,026,176)			(2,026,176)
Ending balance, shares at Jun. 30, 2018	2,774,394	810,856
Ending balance, value at Jun. 30, 2018	$ 2,774	$ 811	167,590,260	(149,781,831)	253,734	(5,281,180)	12,784,568
Beginning balance, shares at Dec. 31, 2018	2,774,394	810,856
Beginning balance, value at Dec. 31, 2018	$ 2,774	$ 811	168,170,244	(153,233,595)	253,734	(5,281,180)	9,912,788
Issuance of common stock and warrants in registered direct offering, net of issuance costs, shares		86,667
Issuance of common stock and warrants in registered direct offering, net of issuance costs, value		$ 87	2,698,963				2,699,050
Exercise of pre-funded warrants, shares		42,417
Exercise of pre-funded warrant, value		$ 42	467				509
Issuance of common stock to vendor, shares		7,836
Issuance of common stock to vendor, value		$ 7	(7)
Issuance of common stock to adjust for reverse split rounding, shares		1,442
Issuance of common stock to adjust for reverse split rounding, value		$ 1	(1)
Deemed dividend related to Series B Preferred Stock down round provision			3,879,447				3,879,447
Accretion of deemed dividend related to Series B Preferred Stock down round provision			(3,879,447)				(3,879,447)
Conversion of Series B preferred stock to shares of common stock, value							0
Share-based expense			450,667				450,677
Common stock awards to vendors			32,427				32,427
Net loss				(2,704,650)			(2,704,650)
Ending balance, shares at Jun. 30, 2019	2,774,394	949,218
Ending balance, value at Jun. 30, 2019	$ 2,774	$ 948	171,352,760	(155,938,245)	253,734	(5,281,180)	10,390,791
Beginning balance, shares at Mar. 31, 2019	2,774,394	897,523
Beginning balance, value at Mar. 31, 2019	$ 2,774	$ 898	171,103,147	(154,560,845)	253,734	(5,281,180)	11,518,528
Exercise of pre-funded warrants, shares		42,417
Exercise of pre-funded warrant, value		$ 42	467				509
Issuance of common stock to vendor, shares		7,836
Issuance of common stock to vendor, value		$ 7	(7)				0
Issuance of common stock to adjust for reverse split rounding, shares		1,442
Issuance of common stock to adjust for reverse split rounding, value		$ 1	(1)				0
Share-based expense			234,154				234,154
Common stock awards to vendors			15,000				15,000
Net loss				(1,377,400)			(1,377,400)
Ending balance, shares at Jun. 30, 2019	2,774,394	949,218
Ending balance, value at Jun. 30, 2019	$ 2,774	$ 948	$ 171,352,760	$ (155,938,245)	$ 253,734	$ (5,281,180)	$ 10,390,791