Annual report pursuant to Section 13 and 15(d)

12. Commitments and Contingent Liabilities (Details Narrative)

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12. Commitments and Contingent Liabilities (Details Narrative) - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Rent expense $ 100,000 $ 100,000
Eurogentec [Member]    
Settlement expense   $ 600,000
Lexington Lease [Member]    
Lease start date Jan. 01, 2014  
Lease termination date Jan. 31, 2019  
Letter of credit $ 66,000  
Letter of credit expiration date May 01, 2019  
Miami, Fl [Member]    
Lease start date Dec. 01, 2016  
Lease termination date Nov. 30, 2019  
Framingham Lease [Member] | Subsequent Event [Member]    
Lease start date Feb. 01, 2019  
Lease termination date Sep. 30, 2020  
Operating lease due in 2019 and 2020 $ 50,000