Annual report pursuant to Section 13 and 15(d)

Document and Entity Information

Document and Entity Information - USD ($)
12 Months Ended
Dec. 31, 2016
Mar. 30, 2017
Jun. 30, 2016
Document And Entity Information [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Period End Date Dec. 31, 2016    
Document Fiscal Year Focus 2016    
Document Fiscal Period Focus FY    
Trading Symbol XBIO    
Entity Registrant Name Xenetic Biosciences, Inc.    
Entity Central Index Key 0001534525    
Current Fiscal Year End Date --12-31    
Entity Filer Category Smaller Reporting Company    
Entity Common Stock, Shares Outstanding   8,652,541  
Current Reporting Status Yes    
Well known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Public Float     $ 13,978,386