EXHIBIT 31.5
CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER
PURSUANT TO EXCHANGE ACT RULES 13a-14(a) AND 15d-14(a),
AS ADOPTED PURSUANT TO
SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002
I, James Parslow, certify that:
| 1. | I have reviewed this Amendment No. 2 to the annual report on Form 10-K of Xenetic Biosciences, Inc.; and | 
| 2. | Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report. | 
Dated: May 13, 2025
| By: | /s/ James Parslow | 
| James Parslow | |
| Interim Chief Executive Officer | |
| (Principal Executive Officer) |