October 28, 2016

VIA EDGAR AND E-MAIL

United States Securities and Exchange Commission
Attention:     Suzanne Hayes, Assistant Director, Office of Healthcare and Insurance

Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549-6010

 Ladies and Gentlemen:

We hereby request withdrawal of our previous request for acceleration of the above-referenced Registration Statement, which was dated October 26, 2016.

Thank you for your assistance in this matter.

Very truly yours,

Xenetic Biosciences, Inc.

By:  /s/ M. Scott Maguire                           

Michael Scott Maguire   

Chief Executive Officer