Exhibit 1

JOINT FILING AGREEMENT

In accordance with Rule 13d-1(k)(1)(iii) promulgated under the Securities Exchange Act of 1934, as amended, the undersigned company and individuals agree to the joint filing on behalf of each of them of a Schedule 13D (including amendments thereto) with respect to the Common Stock of Xenetic Biosciences, Inc. This Joint Filing Agreement shall be filed as an Exhibit to such Statement.

	June 14, 2023
	Date

	CLS Therapeutics, LLC.

	/s/ Georgy Tets
	Signature

	Georgy Tets, MD, PhD, Chief Executive Officer
	Name/Title

	CLS Therapeutics, LLC

	/s/ Georgy Tets
	Signature

	Georgy Tets, MD, PhD, Director
	Name/Title

	/s/ Dmitry Genkin
	Signature

	Dmitry Genkin
	Name

	/s/ Victor Tets
	Signature

	Victor Tets
	Name

	/s/ Georgy Tets
	Signature

	Georgy Tets, MD, PhD
	Name

	/s/ M. Scott Maguire
	Signature

	M. Scot Maguire
	Name